Best Stain-Removing Detergents

Looking for the best stain-removing detergent? Discover our top 10 picks that tackle even the toughest stains with ease, keeping your laundry fresh and clean without breaking the bank.

Stains happen, but they don’t have to stick around. Finding the best stain-removing detergent can save your clothes and your wallet. Let’s dive into the top picks that tackle tough stains with ease.

From grass to grease, these detergents work hard so you don’t have to. They’re trusted, powerful, and affordable. Say goodbye to stubborn stains for good.

Whether it’s pet messes or sweat, these products deliver fresh, clean results. Ready to transform your laundry routine? Let’s get started!

List of Top 10 Stain-Removing Detergents

Image Title Best For Price
ARM & HAMMER Plus OxiClean Stain Fighters Liquid Laundry Detergent, Fresh Scent, 166.5 fl oz, 128 Loads ARM & HAMMER Plus OxiClean Stain Fighters Liquid Laundry Detergent, Fresh Scent, 166.5 fl oz, 128 Loads

This ARM & HAMMER Plus OxiClean Laundry Detergent is perfect for busy families and anyone who wants sparkling clean clothes without the fuss. It’s ideal for tackling tough stains and keeping your laundry fresh and bright, making wash day a breeze.

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Enzyme Laundry Booster Odor Remover - 2 lbs Unscented Enzymatic Clothes Stain Cleaner Powder, Natural Deodorizer with Bio Active Enzymes, Detergent Additive Eliminator for Sweat, Oil, Blood - 64 Loads Enzyme Laundry Booster Odor Remover – 2 lbs Unscented Enzymatic Clothes Stain Cleaner Powder, Natural Deodorizer with Bio Active Enzymes, Detergent Additive Eliminator for Sweat, Oil, Blood – 64 Loads

This product is perfect for anyone with tough stains or strong odors in their laundry. It’s ideal for removing sweat, oil, blood, or grease without harsh chemicals. Works on all fabrics, keeps whites bright, and lasts for 64 loads.

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Nature’s Miracle Laundry Boost In-Wash Stain and Odor Remover, 32 Ounces, Laundry Stain and Odor Removing Additive For All Machines Nature’s Miracle Laundry Boost In-Wash Stain and Odor Remover, 32 Ounces, Laundry Stain and Odor Removing Additive For All Machines

Pet owners dealing with tough stains and odors from urine, feces, or vomit will find this product ideal. Its bio-enzymatic formula safely breaks down messes on clothes and pet beds while being gentle on fabrics and safe for pets. OdorCapture 360 Technology ensures freshness, and it works in all washing machines.

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ARM & HAMMER Plus OxiClean with Odor Blasters Liquid Laundry Detergent, Laundry Odor Remover, Attacks Stains, Fresh Burst Scent, 74 Loads, 96.2 Fl Oz ARM & HAMMER Plus OxiClean with Odor Blasters Liquid Laundry Detergent, Laundry Odor Remover, Attacks Stains, Fresh Burst Scent, 74 Loads, 96.2 Fl Oz

This detergent is perfect for anyone who wants fresh, clean laundry. It’s great for removing tough odors like pet smells, sweat, or musty towels.

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Tide Ultra Oxi Boost Liquid Laundry Detergent, 148 fl oz, 105 Loads, Advanced Stain Remover with Extra Oxi Power Tide Ultra Oxi Boost Liquid Laundry Detergent, 148 fl oz, 105 Loads, Advanced Stain Remover with Extra Oxi Power

This product is perfect for anyone fighting tough stains without pre-treating. It’s ideal for those who want stronger cleaning power than baking soda-based detergents and need an easy-pour cap for mess-free use.

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ARM & HAMMER Plus OxiClean with Odor Blasters Liquid Laundry Detergent, Laundry Odor Remover, Attacks Stains, Fresh Burst Scent, 154 Loads, 200.2 Fl Oz ARM & HAMMER Plus OxiClean with Odor Blasters Liquid Laundry Detergent, Laundry Odor Remover, Attacks Stains, Fresh Burst Scent, 154 Loads, 200.2 Fl Oz

This detergent is perfect for people who need tough odor removal. It attacks stains and kills strong smells like pet odors, sweat, or musty towels. Its 3X odor power and OxiClean formula leave clothes fresh and clean. Fresh Burst Scent adds a lasting clean feel. Trusted by many, it’s ideal for heavy-duty laundry needs.

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Tide Ultra Oxi Boost Liquid Laundry Detergent, 132 fl oz, 94 Loads, Advanced Stain Remover, Laundry Detergent Liquid with Extra Oxi Power Tide Ultra Oxi Boost Liquid Laundry Detergent, 132 fl oz, 94 Loads, Advanced Stain Remover, Laundry Detergent Liquid with Extra Oxi Power

Busy households needing tough stain removal without pre-treating will love this detergent. It works in any machine, handles 94 loads, and delivers extra oxi power for deep cleaning.

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ARM & HAMMER Plus OxiClean Odor Blasters Fresh Burst, 77 Loads Liquid Laundry Detergent, 100.5 Fl oz ARM & HAMMER Plus OxiClean Odor Blasters Fresh Burst, 77 Loads Liquid Laundry Detergent, 100.5 Fl oz

ARM & HAMMER Plus OxiClean Odor Blasters is perfect for those tackling tough odors and stubborn stains. It’s ideal for active families, gym-goers, or anyone needing deep cleaning and a fresh scent that lasts.

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OxiClean Triple Action White Revive Laundry Whitener and Stain Remover Powder, Use with Detergent, Whitens and Brightens Clothes, Removes Tough Stains, Color Safe, Chlorine Free, 4 lbs OxiClean Triple Action White Revive Laundry Whitener and Stain Remover Powder, Use with Detergent, Whitens and Brightens Clothes, Removes Tough Stains, Color Safe, Chlorine Free, 4 lbs

This product is perfect for anyone who wants brighter whites, vivid colors, and tough stains gone fast. Ideal for families, athletes, or busy households needing a safe, chlorine-free boost for laundry.

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ARM & HAMMER Plus OxiClean Ultra Stain Fighters Liquid Laundry Detergent, Stain Remover for Clothes, Fresh Scent, 74 Loads, 96.2 Fl Oz ARM & HAMMER Plus OxiClean Ultra Stain Fighters Liquid Laundry Detergent, Stain Remover for Clothes, Fresh Scent, 74 Loads, 96.2 Fl Oz

This product is perfect for busy families and active individuals who need powerful stain removal. It attacks over 101 stains with OxiClean power, leaving clothes fresh and clean.

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Detailed Reviews

Discover the top 10 stain-removing detergents in our expert-picked guide. Each product is thoroughly reviewed for performance and value. Find the perfect match for your laundry needs, whether you prioritize comfort or affordability. Read on to transform your laundry routine with confidence and ease.

1. ARM & HAMMER Plus OxiClean Stain Fighters Liquid Laundry Detergent, Fresh Scent, 166.5 fl oz, 128 Loads

ARM & HAMMER Plus OxiClean Stain Fighters Liquid Laundry Detergent, Fresh Scent, 166.5 fl oz, 128 Loads

This liquid laundry detergent tackles stains, fights odors, and brightens clothes. It cleans 128 medium loads per 166.5 fl oz bottle. With ARM & HAMMER Baking Soda and OxiClean, it removes over 101 stains like food, grass, and grease.

The low-suds formula works in standard and HE washers without clogging sensors. It’s trusted for deep cleaning, freshness, and saving money over time.

Pros Cons
  • Removes 101+ stains with OxiClean power.
  • Fresh scent and lasting freshness for all clothes.
  • Safe for HE machines, no sensor blockage.
  • Whitens whites, brightens colors in one wash.
  • Large bottle may be hard to handle for some users.
  • Fresh scent might be too strong for sensitive noses.
  • Price could be higher than basic detergents.

Perfect For:

This ARM & HAMMER Plus OxiClean Laundry Detergent is perfect for busy families and anyone who wants sparkling clean clothes without the fuss. It’s ideal for tackling tough stains and keeping your laundry fresh and bright, making wash day a breeze.

Ready to Purchase?

2. Enzyme Laundry Booster Odor Remover – 2 lbs Unscented Enzymatic Clothes Stain Cleaner Powder, Natural Deodorizer with Bio Active Enzymes, Detergent Additive Eliminator for Sweat, Oil, Blood – 64 Loads

Enzyme Laundry Booster Odor Remover - 2 lbs Unscented Enzymatic Clothes Stain Cleaner Powder, Natural Deodorizer with Bio Active Enzymes, Detergent Additive Eliminator for Sweat, Oil, Blood - 64 Loads

ACTIVE Enzyme Laundry Booster removes tough stains and odors. It works with your detergent to fight sweat, blood, oil, and grease. This unscented powder uses natural enzymes, not harsh chemicals.

Safe for all fabrics, including delicate activewear and bright colors. The plant-based formula is gentle yet powerful.

Just add to your wash for 64 loads of freshness. Works in any washer type—HE, front, or top-load. Also doubles as a soak or pretreat booster for stubborn stains.

Pros Cons
  • Targets stains & odors with bio enzymatic power, not just masking smells.
  • Removes grease, sweat, blood stains effortlessly, even tough, set-in marks.
  • Safe for all fabrics, including activewear, with plant-based formula.
  • 64 loads per 32-oz package – more cost-effective than smaller sizes.
  • Works with any washer & detergent, including HE machines.
  • No scent may disappoint those who prefer fresh fragrances.
  • Larger size might take up extra storage space.
  • Powder form could be messier than liquid alternatives.

Perfect For:

This product is perfect for anyone with tough stains or strong odors in their laundry. It’s ideal for removing sweat, oil, blood, or grease without harsh chemicals. Works on all fabrics, keeps whites bright, and lasts for 64 loads.

Ready to Purchase?

3. Nature’s Miracle Laundry Boost In-Wash Stain and Odor Remover, 32 Ounces, Laundry Stain and Odor Removing Additive For All Machines

Nature’s Miracle Laundry Boost In-Wash Stain and Odor Remover, 32 Ounces, Laundry Stain and Odor Removing Additive For All Machines

Nature’s Miracle Laundry Boost is a powerful stain and odor remover. It’s designed to tackle tough pet messes in your laundry.

This formula uses bio-enzymes to break down stains like urine, vomit, and grass. It’s safe for pets and homes and works in all washing machines.

The product is gentle on fabrics but avoids specialty materials. It includes OdorCapture 360 Technology for fresh results. Use it with your regular detergent for best results.

Pros Cons
  • Destroys tough pet stains and odors.
  • Gentle on most fabrics.
  • Safe for pets and home.
  • Neutralizes odors with advanced technology.
  • Works in all washing machines.
  • Not for special fabrics like silk, wool, or leather.
  • Doesn’t replace your regular laundry detergent.
  • Avoid using on fluorescent or khaki items.

Perfect For:

Pet owners dealing with tough stains and odors from urine, feces, or vomit will find this product ideal. Its bio-enzymatic formula safely breaks down messes on clothes and pet beds while being gentle on fabrics and safe for pets. OdorCapture 360 Technology ensures freshness, and it works in all washing machines.

Ready to Purchase?

4. ARM & HAMMER Plus OxiClean with Odor Blasters Liquid Laundry Detergent, Laundry Odor Remover, Attacks Stains, Fresh Burst Scent, 74 Loads, 96.2 Fl Oz

ARM & HAMMER Plus OxiClean with Odor Blasters Liquid Laundry Detergent, Laundry Odor Remover, Attacks Stains, Fresh Burst Scent, 74 Loads, 96.2 Fl Oz

ARM & HAMMER Plus OxiClean is a powerful laundry detergent. It comes in a 96.2 fl oz bottle. This size is perfect for 74 loads of laundry.

It has 3X odor-fighting power. This means it tackles tough smells like pet odors and sweat. Your clothes will feel fresh and clean after each wash.

This detergent is dermatologist-tested. It boosts lasting freshness and removes stains. Trust ARM & HAMMER for a reliable, trusted clean.

Pros Cons
  • Removes tough odors like pet smells and sweat.
  • 3X odor power fights stubborn smells effectively.
  • Fights stains and odors with OxiClean power.
  • Leaves clothes fresh and odor-free after washing.
  • Trusted brand with top-selling laundry detergent.
  • Not for sensitive skin.
  • Strong scent may not suit everyone.
  • Might be pricier than basic detergents.

Perfect For:

This detergent is perfect for anyone who wants fresh, clean laundry. It’s great for removing tough odors like pet smells, sweat, or musty towels.

Ready to Purchase?

5. Tide Ultra Oxi Boost Liquid Laundry Detergent, 148 fl oz, 105 Loads, Advanced Stain Remover with Extra Oxi Power

Tide Ultra Oxi Boost Liquid Laundry Detergent, 148 fl oz, 105 Loads, Advanced Stain Remover with Extra Oxi Power

Tide Ultra Oxi Boost Liquid Laundry Detergent is a powerful cleaner. It removes tough stains with extra Oxi power.

This detergent skips pre-treating. It has 2x cleaning ingredients. The easy-pour cap makes measuring simple.

Tide is a trusted brand. Dermatologists recommend it. One bottle washes 105 loads.

Pros Cons
  • Extra Oxi Power fights tough stains effectively.
  • No pre-treating needed for set-in stains.
  • 2x cleaning power vs. baking soda brands.
  • Easy-pour cap simplifies measuring and use.
  • Trusted dermatologist-recommended formula for safe, strong cleaning.
  • High price per ounce compared to basic detergents.
  • Strong scent may irritate sensitive skin.
  • Liquid mess can stain surfaces if spilled.

Perfect For:

This product is perfect for anyone fighting tough stains without pre-treating. It’s ideal for those who want stronger cleaning power than baking soda-based detergents and need an easy-pour cap for mess-free use.

Ready to Purchase?

6. ARM & HAMMER Plus OxiClean with Odor Blasters Liquid Laundry Detergent, Laundry Odor Remover, Attacks Stains, Fresh Burst Scent, 154 Loads, 200.2 Fl Oz

ARM & HAMMER Plus OxiClean with Odor Blasters Liquid Laundry Detergent, Laundry Odor Remover, Attacks Stains, Fresh Burst Scent, 154 Loads, 200.2 Fl Oz

Tired of stubborn odors clinging to your clothes? ARM & HAMMER Plus OxiClean with Odor Blasters is here to save the day! This powerful liquid laundry detergent tackles even the most challenging smells, leaving your laundry amazingly fresh.

It has 3X odor power. It blasts away tough stains. Your clothes will smell incredibly clean.

Pros Cons
  • Removes tough odors like pet smells, sweat, and musty towels fast.
  • 3X odor power fights more smells per load than regular detergents.
  • Fresh Burst Scent keeps clothes smelling clean all day.
  • OxiClean boosts stain removal and lasting freshness in every wash.
  • Trusted brand used in 154 loads per big 200.2 fl oz bottle.
  • Strong scent may be too overpowering for sensitive noses.
  • Large bottle takes up significant storage space in small homes.
  • Not eco-friendly packaging, uses more plastic than needed.

Perfect For:

This detergent is perfect for people who need tough odor removal. It attacks stains and kills strong smells like pet odors, sweat, or musty towels. Its 3X odor power and OxiClean formula leave clothes fresh and clean. Fresh Burst Scent adds a lasting clean feel. Trusted by many, it’s ideal for heavy-duty laundry needs.

Ready to Purchase?

7. Tide Ultra Oxi Boost Liquid Laundry Detergent, 132 fl oz, 94 Loads, Advanced Stain Remover, Laundry Detergent Liquid with Extra Oxi Power

Tide Ultra Oxi Boost Liquid Laundry Detergent, 132 fl oz, 94 Loads, Advanced Stain Remover, Laundry Detergent Liquid with Extra Oxi Power

Tide Ultra Oxi Boost Liquid Laundry Detergent has extra Oxi power to tackle tough stains without pre-treating. Its 132 fl oz size handles up to 94 loads, offering long-lasting value.

The easy-pour cap makes measuring simple. It works in both high-efficiency and standard washing machines. This detergent delivers strong cleaning with 2X the cleaning ingredients versus leading baking soda brands.

Pros Cons
  • Super Oxi power for tough stains.
  • Skip pretreating, save time.
  • Twice the cleaning power.
  • Easy pour cap for convenience.
  • Great value with 94 loads.
  • Large bottle may be heavy and hard to handle.
  • Strong scent might not suit sensitive noses.
  • Price could be higher than basic detergents.

Perfect For:

Busy households needing tough stain removal without pre-treating will love this detergent. It works in any machine, handles 94 loads, and delivers extra oxi power for deep cleaning.

Ready to Purchase?

8. ARM & HAMMER Plus OxiClean Odor Blasters Fresh Burst, 77 Loads Liquid Laundry Detergent, 100.5 Fl oz

ARM & HAMMER Plus OxiClean Odor Blasters Fresh Burst, 77 Loads Liquid Laundry Detergent, 100.5 Fl oz

ARM & HAMMER Plus OxiClean Odor Blasters Fresh Burst is a liquid laundry detergent that cleans 77 medium loads. It fights tough odors, removes stains, and leaves clothes smelling fresh.

ARM & HAMMER Baking Soda powers deep cleaning. OxiClean Stain Fighters blast away food, grass, and grease. Odor Blasters tackle sweat and musty smells fast.

This detergent is strong yet affordable. Trusted for generations, it keeps clothes clean, fresh, and lasting longer.

Pros Cons
  • Fights tough odors and leaves clothes smelling fresh.
  • Blasts away stains like grass, grease, and food.
  • Deep cleans with trusted ARM & HAMMER Baking Soda.
  • Lasting freshness for 77 loads in one bottle.
  • Strong scent may be too overpowering for some users.
  • Large bottle takes up significant storage space in small homes.
  • Not suitable for all fabric types, check labels first.

Perfect For:

ARM & HAMMER Plus OxiClean Odor Blasters is perfect for those tackling tough odors and stubborn stains. It’s ideal for active families, gym-goers, or anyone needing deep cleaning and a fresh scent that lasts.

Ready to Purchase?

9. OxiClean Triple Action White Revive Laundry Whitener and Stain Remover Powder, Use with Detergent, Whitens and Brightens Clothes, Removes Tough Stains, Color Safe, Chlorine Free, 4 lbs

OxiClean Triple Action White Revive Laundry Whitener and Stain Remover Powder, Use with Detergent, Whitens and Brightens Clothes, Removes Tough Stains, Color Safe, Chlorine Free, 4 lbs

OxiClean Triple Action White Revive keeps whites brilliant and colors bright. It removes tough stains like oil, coffee, and grass. Use it with your detergent for better results.

This color-safe powder works in all washers and temperatures. The resealable pouch is easy to use and ship-friendly.

Pros Cons
  • Whitens and brightens clothes, keeping them looking new.
  • Removes tough stains like oil, coffee, and grass effortlessly.
  • Color-safe and chlorine-free, perfect for all fabrics.
  • Easy to use in any washer, even with cold water.
  • Portable, resealable pouch for convenient storage and travel.
  • Large pouch may be too bulky for small spaces.
  • Requires additional detergent use for effectiveness.
  • Possible fabric fading with prolonged use.

Perfect For:

This product is perfect for anyone who wants brighter whites, vivid colors, and tough stains gone fast. Ideal for families, athletes, or busy households needing a safe, chlorine-free boost for laundry.

Ready to Purchase?

10. ARM & HAMMER Plus OxiClean Ultra Stain Fighters Liquid Laundry Detergent, Stain Remover for Clothes, Fresh Scent, 74 Loads, 96.2 Fl Oz

ARM & HAMMER Plus OxiClean Ultra Stain Fighters Liquid Laundry Detergent, Stain Remover for Clothes, Fresh Scent, 74 Loads, 96.2 Fl Oz

ARM & HAMMER Plus OxiClean Ultra Stain Fighters Liquid Laundry Detergent tackles tough stains. This 96.2 fl oz bottle handles 74 loads. It leaves clothes fresh with a clean scent.

3X stain fighters work harder than regular detergents. 5 in 1 power cleans, whitens, and brightens clothes. It beats over 101 stains like food, grass, and grease.

ARM & HAMMER is the #1 liquid laundry brand. This detergent is Trusted Clean and easy to use. It keeps fabrics fresh, soft, and looking new.

Pros Cons
  • 3X stain fighters tackle tough stains fast
  • 5-in-1 power cleans, whitens, and freshens clothes
  • Removes 101+ stains like food, grass, and oil
  • Trusted #1 brand for effective laundry care
  • Long-lasting with 74 loads per bottle
  • Strong scent may be too overpowering for sensitive noses.
  • Large bottle takes up significant storage space in small homes.
  • Not for delicates, may damage fine or hand-wash fabrics.

Perfect For:

This product is perfect for busy families and active individuals who need powerful stain removal. It attacks over 101 stains with OxiClean power, leaving clothes fresh and clean.

Ready to Purchase?

Buying Guide

Stains happen, but the right detergent can save your clothes. Finding the best stain-removing detergent keeps your laundry fresh and clean. Let’s explore what makes a great choice.

Engaging Experience:
Imagine tackling tough stains with ease. No more scrubbing or rewashing. These detergents work hard so you don’t have to, leaving your clothes spotless and smelling great.

Factors to Consider When Buying:
Stain Type: Choose a detergent that targets your common stains, like grass, grease, or pet messes.
Fabric Safety: Ensure it’s safe for all fabrics, especially delicate or bright-colored items.
Machine Compatibility: Check if it works in your washer type—HE, front-load, or top-load.
Scent Preference: Opt for fresh, unscented, or odor-fighting formulas based on your needs.
Value for Money: Look for detergents that clean many loads without breaking the bank.
Eco-Friendly: Consider plant-based or natural formulas if you prefer greener options.
Ease of Use: Choose detergents with simple measuring or pre-treat options for convenience.